Researchers investigate protein phosphatase to identify new treatments for cancer, other diseases
The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential. It is also known to perform important functions in cells under normal conditions, participating in both the proliferation process and the regulation of intracellular systems. Research continues on its role in cancer progression.
In Brazil, a group of researchers at the University of Campinas s In Vitro Bioassay and Signal Transduction Laboratory led by Professor Carmen Veríssima Ferreira-Halder are studying the possibility of inhibiting this protein phosphatase to create novel opportunities for monitoring and treatment of cancer and other diseases.
Η Παλμέρας του Αμπέλ Φερέιρα στον τελικό του Κόπα Λιμπερταδόρες
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Κόπα Λιμπερταδόρες: Ο Φερέιρα οδήγησε την Παλμέιρας στον τελικό, έπειτα από 20 χρόνια | ΣΠΟΡ
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Study shows how intestinal stem cells constantly renew and give rise to specialized cell types
The gut plays a central role in the regulation of the body s metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide.
Targeting endocrine dysfunction at an early stage by stimulating the formation of specific enteroendocrine cells from intestinal stem cells could be a promising regenerative approach for diabetes therapy. For this, however, a detailed understanding of the intestinal stem cell lineage hierarchy and the signals regulating the recruitment of the different intestinal cell types is critical.
Are you at risk?
The exact cause of bowel cancer is unknown. However, research has shown several factors may make you more likely to develop it.
Your risk of developing bowel (colon and rectal) cancer depends on many things including age, genetics and lifestyle factors.
Having one or more risk factors doesn’t mean that you will definitely get bowel cancer.
Bowel cancer risk: Eating lots of red and processed meat increases the risk (Image: Getty Images)
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One modifiable risk factor relates to the foods you eat.
Many studies have shown that eating lots of red and processed meat increases the risk of bowel cancer.